Research on bio pesticides from medicinal and herbal plants extracts from the Mediterranean nature, and monitoring insecticides residues in nature and food chain for maintaining sustainable agricultural systems by using bio insecticides as alternative to insecticides to save the land and water resources and the crop product from the pollution, and also the agricultural ecosystem saving the natural enemies and other organisms found the the ecosystem such as beneficial insects as pollinators especially the honeybees which suffers a lot from pollution from the used insecticides like the Neonicotinoids which include acetamiprid, clothianidin, imidacloprid, nitenpyram, nithiazine, thiacloprid and thiamethoxam. Imidacloprid has been the most widely used insecticide in the world from 1999 through at least 2018. Neonicotinoid use has been studied in relation to adverse ecological effects, including honey-bee colony collapse disorder (CCD), and declining populations of insect-eating birds.
