Arid regions are increasingly exposed to severe environmental constraints, including recurrent droughts, desertification, and the overexploitation of water resources. In parallel, the growing demand for food and energy places additional pressure on already fragile ecosystems. Addressing these interconnected challenges requires innovative and integrated solutions capable of ensuring sustainable agricultural production while preserving natural resources. In this context, the present proposal aims to develop and assess sustainable agricultural systems tailored to arid environments, while simultaneously contributing to renewable energy generation. The first system investigated is agrivoltaics, which integrates agricultural production with photovoltaic electricity generation by installing solar panels above crops on the same land. This approach represents a synergistic interaction between photosynthesis and solar energy conversion. Agrivoltaic systems are particularly relevant for arid regions, where agricultural productivity is constrained by water scarcity and extreme temperatures. By addressing the water–energy–food nexus, this system enhances the resilience of both food and energy supply chains. The partial shading provided by photovoltaic panels reduces direct solar radiation, thereby limiting soil water evaporation and mitigating plant heat stress. This results in improved microclimatic conditions that can enhance crop productivity. Simultaneously, the vegetation-induced cooling effect contributes to lowering photovoltaic module temperatures, thus improving their electrical efficiency. The second system focuses on hydroponics, an innovative soilless cultivation technique that offers a sustainable alternative to conventional greenhouse agriculture. Traditional greenhouse systems in arid regions often suffer from high temperatures and humidity, which favor the proliferation of pests and diseases. In contrast, hydroponic systems enable precise control of water and nutrient delivery, significantly improving water-use efficiency and fertilizer management while ensuring consistent crop yields in constrained environments. The integration of intelligent microclimate control strategies will address seasonal challenges, such as low temperatures and excessive humidity during winter, thereby enabling optimized, year-round agricultural production.