The collaboration sought concerns joining a network of scientists working on developing new tools and highly efficient novel and targeted drugs against plant or animal microbial pathogens.
DESCRIPTION OF YOUR ORGANISATION:
The Aspergillus Genetics Lab (AGL) is established in the Department of Biology of the National and Kapodistrian University of Athens (http://en.uoa.gr/), the biggest and oldest University of Greece, known for its excellent record in basic research in all areas of science and arts. The major interests AGL concern basic studies related to the regulation of cellular expression, structure, function and evolution of transmembrane transporters, as well as, to the channeling of basic knowledge on transporters to research concerning the prevention of plant and animal microbial diseases. We use fungi as model systems for: a) genetically, biochemically and functionally dissecting structure-function relationships underlying purine-pyrimidine transporter kinetics, specificity and molecular evolution, b) identifying the pathways and molecular mechanisms involved in the membrane trafficking, endocytosis and turnover of specific transporters in response to various physiological, developmental and genetic signals, c) studying the role of transporters in fungal pathogenicity and use in silico modeling of specific purine transporters for rational antifungal drug design.
The Partnership for Research and Innovation in the Mediterranean Area will devise new R&I approaches to improve water availability and sustainable agriculture production in a region heavily distressed by climate change, urbanisation and population growth
The PRIMA programme is an Art.185 initiative supported and funded under Horizon 2020, the European Union’s Framework Programme for Research and Innovation.